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Altromycins, novel pluramycin-like antibiotics. I. Taxonomy of the producing organism, fermentation and antibacterial activity.

1990; Springer Nature; Volume: 43; Issue: 3 Linguagem: Inglês

10.7164/antibiotics.43.223

1881-1469

MARIANNA JACKSON, James P. Karwowski, Robert J. Theriault, Dwight J. Hardy, Sue Swanson, GRANT J. BARLOW, PAULINE M. TILLIS, James B. McAlpine,

Marine Sponges and Natural Products

The altromycins are novel anthraquinone-derived antibiotics related to the pluramycins. They are produced by an actinomycete, AB 1246E-26, which was isolated from a South African bushveld soil. The altromycins have Gram-positive antibacterial activity with MICs of 0.2 to 3.12 μg/ml against Streptococci and Staphylococci.