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Working memory and left medial temporal cortical thickness

2016; Thieme Medical Publishers (Germany); Volume: 74; Issue: 10 Linguagem: Inglês

10.1590/0004-282x20160123

1678-4227

Giuseppe Pastura, Tadeu Takao Almodovar Kubo, Maria Angélica Regalla, Cíntia Mesquita, Gabriel Coutinho, Emerson L. Gasparetto, Otávio Figueiredo, Paulo Mattos, Abelardo Araújo,

Attention Deficit Hyperactivity Disorder

To perform a pilot study to investigate the association between working memory and cortical thickness in a sample of attention deficit/hyperactivity disorder (ADHD) children.Seventeen children aged 7-10 years diagnosed with ADHD and 16 healthy children underwent a magnetic resonance scan for cortical thickness measurements. Data was correlated with working memory performance using the Backwards Digit Span subtest of the Wechsler Intelligence Scale for Children.Working memory impairment, evidenced by lower scores on the Backwards Digit Span, was observed in patients with ADHD compared to healthy controls. There was a direct correlation between working memory and cortical thickness of the left medial temporal lobe (Spearman's correlation coefficient: 0.499; p < 0.005).Our data suggests, for the first time, a correlation between working memory, evaluated by the Backwards Digit Span, and left medial temporal cortical thickness.