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Chordomas and chondrosarcomas-The role of radiation therapy

2016; Wiley; Volume: 114; Issue: 5 Linguagem: Inglês

10.1002/jso.24368

1096-9098

Karen De Amorim Bernstein, Thomas F. DeLaney,

Oral and Maxillofacial Pathology

Journal of Surgical OncologyVolume 114, Issue 5 p. 564-569 Review Article Chordomas and chondrosarcomas—The role of radiation therapy Karen De Amorim Bernstein MD, Corresponding Author Karen De Amorim Bernstein MD kbernstein@mgh.harvard.edu Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts Correspondence to: Karen De Amorim Bernstein, MD, Massachusetts General Hospital/Harvard Medical School, 30 Fruit Street, Boston, MA 02114. Fax: +1-617-724-9532. E-mail: kbernstein@mgh.harvard.eduSearch for more papers by this authorThomas DeLaney MD, Thomas DeLaney MD Massachusetts General Hospital/Harvard Medical School, Boston, MassachusettsSearch for more papers by this author Karen De Amorim Bernstein MD, Corresponding Author Karen De Amorim Bernstein MD kbernstein@mgh.harvard.edu Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts Correspondence to: Karen De Amorim Bernstein, MD, Massachusetts General Hospital/Harvard Medical School, 30 Fruit Street, Boston, MA 02114. Fax: +1-617-724-9532. E-mail: kbernstein@mgh.harvard.eduSearch for more papers by this authorThomas DeLaney MD, Thomas DeLaney MD Massachusetts General Hospital/Harvard Medical School, Boston, MassachusettsSearch for more papers by this author First published: 19 October 2016 https://doi.org/10.1002/jso.24368Citations: 31Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Abstract Achieving negative surgical margins can be challenging for skull base and spinal/paraspinal sarcomas. Data shows that pre- or post-operative radiation therapy improves local control. Delivery of sufficient dose of radiation can be difficult because of the proximity to normal organs/tissues that are sensitive to radiation therapy and therefore dose-limiting. A comprehensive literature search was conducted using PubMed search engine. The scarcity of prospective, randomized data limits the ability to generate definitive treatment recommendations. J. Surg. Oncol. 2016;114:564–569. © 2016 Wiley Periodicals, Inc. Citing Literature Volume114, Issue5October 1, 2016Pages 564-569 RelatedInformation