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BIBTEX RIS

Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade

2016; American Association for the Advancement of Science; Volume: 354; Issue: 6316 Linguagem: Inglês

10.1126/science.aaf2807

ISSN

1095-9203

Autores

Kristen E. Pauken, Morgan A. Sammons, Pamela M. Odorizzi, Sasikanth Manne, Jernej Godec, Omar Khan, Adam Drake, Zeyu Chen, Debattama R. Sen, Makoto Kurachi, R. Anthony Barnitz, Caroline Bartman, Bertram Bengsch, Alexander C. Huang, Jason M. Schenkel, Golnaz Vahedi, W. Nicholas Haining, Shelley L. Berger, E. John Wherry,

Tópico(s)

Immunotherapy and Immune Responses

Resumo

Epigenetic profiling suggests that exhausted T cells are a distinct cell linage.

Referência(s)