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Necrotizing pancreatitis: challenges and solutions

2016; Dove Medical Press; Volume: Volume 9; Linguagem: Inglês

10.2147/ceg.s99824

1178-7023

Victoria A. Bendersky, Mohan K. Mallipeddi, Alexander Perez, Theodore N. Pappas,

Pancreatic and Hepatic Oncology Research

Abstract: Acute pancreatitis is a common disease that can progress to gland necrosis, which imposes significant risk of morbidity and mortality. In general, the treatment for pancreatitis is a supportive therapy. However, there are several reasons to escalate to surgery or another intervention. This review discusses the pathophysiology as well as medical and interventional management of necrotizing pancreatitis. Current evidence suggests that patients are best served by delaying interventions for at least 4 weeks, draining as a first resort, and debriding recalcitrant tissue using minimally invasive techniques to promote or enhance postoperative recovery while reducing wound-related complications. Keywords: necrotizing pancreatitis, pancreatic necrosectomy, VARD, pancreatic debridement, pancreatic collections