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Phenotype-based variation as a biomarker of sensitivity to molecularly targeted therapy in melanoma

2016; Royal Society of Chemistry; Volume: 8; Issue: 1 Linguagem: Inglês

10.1039/c6md00466k

2040-2511

Kerem Mert Senses, Mehdi Ghasemi, Muhammad Waqas Akbar, Murat İşbilen, Anna Lucia Fallacara, Shoshana Frankenburg, Silvia Schenone, Michal Lotem, Maurizio Botta, Ali O. Güre,

CAR-T cell therapy research

Transcriptomic phenotypes defined for melanoma have been reported to correlate with sensitivity to various drugs. In this study, we aimed to define a minimal signature that could be used to distinguish melanoma sub-types