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Repeatability of magnetic resonance fingerprinting T 1 and T 2 estimates assessed using the ISMRM/NIST MRI system phantom

2016; Wiley; Volume: 78; Issue: 4 Linguagem: Inglês

10.1002/mrm.26509

1522-2594

Yun Jiang, Dan Ma, Kathryn E. Keenan, Karl F. Stupic, Vikas Gulani, Mark A. Griswold,

MRI in cancer diagnosis

Purpose The purpose of this study was to evaluate accuracy and repeatability of T 1 and T 2 estimates of a MR fingerprinting (MRF) method using the ISMRM/NIST MRI system phantom. Methods The ISMRM/NIST MRI system phantom contains multiple compartments with standardized T 1 , T 2 , and proton density values. Conventional inversion‐recovery spin echo and spin echo methods were used to characterize the T 1 and T 2 values in the phantom. The phantom was scanned using the MRF‐FISP method over 34 consecutive days. The mean T 1 and T 2 values were compared with the values from the spin echo methods. The repeatability was characterized as the coefficient of variation of the measurements over 34 days. Results T 1 and T 2 values from MRF‐FISP over 34 days showed a strong linear correlation with the measurements from the spin echo methods (R 2 = 0.999 for T 1 ; R 2 = 0.996 for T 2 ). The MRF estimates over the wide ranges of T 1 and T 2 values have less than 5% variation, except for the shortest T 2 relaxation times where the method still maintains less than 8% variation. Conclusion MRF measurements of T 1 and T 2 are highly repeatable over time and across wide ranges of T 1 and T 2 values. Magn Reson Med 78:1452–1457, 2017. © 2016 International Society for Magnetic Resonance in Medicine.