Produção Nacional
Revisado por pares
Exercise training improves neurovascular control and calcium cycling gene expression in patients with heart failure with cardiac resynchronization therapy
2016; American Physical Society; Volume: 311; Issue: 5 Linguagem: Inglês
10.1152/ajpheart.00275.2016
ISSN1522-1539
AutoresThais S. Nobre, Lígia M. Antunes‐Correa, Raphaela V. Groehs, Maria Janieire N. N. Alves, Adriana Sarmento de Oliveira, Aline V. N. Bacurau, Úrsula Urias, Guilherme B. Alves, Maria Urbana Pinto Brandão Rondon, Patrı́cia C. Brum, Martino Martinelli Filho, Holly R. Middlekauff, Carlos Eduardo Negrão,
Tópico(s)Cardiovascular and exercise physiology
ResumoHeart failure (HF) is characterized by decreased exercise capacity, attributable to neurocirculatory and skeletal muscle factors. Cardiac resynchronization therapy (CRT) and exercise training have each been shown to decrease muscle sympathetic nerve activity (MSNA) and increase exercise capacity in patients with HF. We hypothesized that exercise training in the setting of CRT would further reduce MSNA and vasoconstriction and would increase Ca
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