Produção Nacional
Epileptic seizures in children with congenital Zika virus syndrome
2016; Instituto Materno Infantil de Pernambuco; Volume: 16; Issue: suppl 1 Linguagem: Inglês
10.1590/1806-9304201600s100003
ISSN1806-9304
AutoresLucas Victor Alves, Danielle Di Cavalcanti Sousa Cruz, Ana Maria Campos van der Linden, Ana Rodrigues Falbo, Maria Júlia Gonçalves de Mello, Camila Esteves Paredes, Germanna Virgínya Cavalcanti Silva, José Natal Figueirôa, Patrícia Gomes de Matos Bezerra,
Tópico(s)Viral Infections and Vectors
ResumoAbstract Objectives: to describe preliminary data referred to epileptic seizures and the probability of occurring these epileptic seizures in the infants' first months of life with congenital Zika virus (ZIKV) syndrome. Methods: concurrent cohort study including newborns and infants with congenital Zika virus syndrome attended at the specialized outpatient clinic at IMIP, Recife, Pernambuco, from October 2015 to May 2016. Results: data on 106 infants were analyzed with confirmed or suspected association to ZIKV infection. Forty children (38.7%) presented an epileptic seizure, classified at 43.3% of the cases as being spasms, 22.7% as generalized tonic seizures, 20.5% as partial and 4.5% other types of seizures. The median of days until the first report on the occurrence of epileptic seizure was 192 days of life. Conclusions: children with congenital Zika virus syndrome presented a high incidence of epileptic seizures before the end of the first semester of life, and spasm was the epileptic seizure mostly observed.
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