Photocatalytic Asymmetric Epoxidation of Terminal Olefins Using Water as an Oxygen Source in the Presence of a Mononuclear Non-Heme Chiral Manganese Complex
2016; American Chemical Society; Volume: 138; Issue: 49 Linguagem: Inglês
10.1021/jacs.6b10836
ISSN1943-2984
AutoresDuyi Shen, Claudio Saracini, Yong‐Min Lee, Wei Sun, Shunichi Fukuzumi, Wonwoo Nam,
Tópico(s)Metalloenzymes and iron-sulfur proteins
ResumoPhotocatalytic enantioselective epoxidation of terminal olefins using a mononuclear non-heme chiral manganese catalyst, [(R,R-BQCN)MnII]2+, and water as an oxygen source yields epoxides with relatively high enantioselectivities (e.g., up to 60% enantiomeric excess). A synthetic mononuclear non-heme chiral Mn(IV)-oxo complex, [(R,R-BQCN)MnIV(O)]2+, affords similar enantioselectivities in the epoxidation of terminal olefins under stoichiometric reaction conditions. Mechanistic details of each individual step of the photoinduced catalysis, including formation of the Mn(IV)-oxo intermediate, are discussed on the basis of combined results of laser flash photolysis and other spectroscopic methods.
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