Addressing the tuberculosis (TB) and diabetes mellitus (DM) co-epidemic among TB patients in Luanda, Angola
2016; Lippincott Williams & Wilkins; Linguagem: Inglês
10.1183/13993003.congress-2016.pa4251
ISSN1531-5487
AutoresGiulia Segafredo, Ugo Fedeli, Anna Maria Gnoni, Filippo Ferretti, Ludovico Corbuccio, Gianluca Quaglio, Luigi Andreoni, Andrea Atzori, Giovanni Putoto,
Tópico(s)Chronic Disease Management Strategies
ResumoBackground Diabetes mellitus (DM) increases the risk of developing active tuberculosis and is associated with worse outcomes. Globally, 15% of tuberculosis cases are estimated to be attributable to diabetes (1). Few epidemiological data about the co-epidemic are available and none in a 22 million country like Angola. Aims and objective We aimed to determine DM prevalence among TB patients accessing to 6 directly observed treatment (DOT) centers in Luanda (Czariango, Luanda and Cacuaco Municipality, Kilamba Kiaxi and Maianga District), Angola. Methods All patient that accessed the 6 DOT centers have been screened for diabetes after being diagnosed of TB. TB diagnosis was preferentially carried out through microscopy, otherwise clinically and radiologically. DM was tested with either Fasting Blood Sugar (considered positive if ≥ 7.0mmol/l) or Random Blood Glucose Test (considered positive if ≥ 11.1mmol/l). The project aims to enroll 7000 patients. Results According to preliminary data, out of 3686 patients, 54% had a positive microscopy test. The crude prevalence of DM among TB patients resulted 7,5%, more than two-fold the prevalence among the general population (3,3%)(2). DM prevalence increased with age, being 4.9% in subjects aged 20-39 and 12.7% in those aged 40-59 years. Conclusions Although data collection still needs to be completed, preliminary findings confirm the high double disease burden. Although challenging, TB and DM services need to be integrated. 1. Riza, A.L. et al. Lancet Diabetes Endocrinol 2014; 2: 74053 2. IDF Atlas, 2015.
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