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Synthesis of 6-methyl-3,4-dihydropyrazinones using an Ugi 4-CR/allenamide cycloisomerization protocol

2016; Royal Society of Chemistry; Volume: 15; Issue: 2 Linguagem: Inglês

10.1039/c6ob02266a

ISSN

1477-0539

Autores

Estefanía Icelo-Ávila, Yoarhy A. Amador‐Sánchez, Luis A. Polindara‐García, Luis D. Miranda,

Tópico(s)

Phytochemical compounds biological activities

Resumo

A two-step synthesis of 6-methyl-3,4-dihydropyrazinones from Ugi adducts and their transformation into pyrazino[2,1- a ]isoindole and pyrazino[2,1- a ]isoquinoline cores has been accomplished.

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