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A Quick Reference on Chloride

2016; Elsevier BV; Volume: 47; Issue: 2 Linguagem: Inglês

10.1016/j.cvsm.2016.10.008

1878-1306

Andrea Bohn, Helio Autrán de Morais,

Renal function and acid-base balance

Chloride is an essential element, playing important roles in digestion, muscular activity, regulation of body fluids, and acid-base balance. As the most abundant anion in extracellular fluid, chloride plays a major role in maintaining electroneutrality. Chloride is intrinsically linked to sodium in maintaining osmolality and fluid balance and has an inverse relationship with bicarbonate in maintaining acid-base balance. It is likely because of these close ties that chloride does not get the individual attention it deserves; we can use these facts to simplify and interpret changes in serum chloride concentrations.