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Beauty in the breakdown: The morphology of the first polar body in mature mouse eggs

2016; Wiley; Volume: 84; Issue: 1 Linguagem: Inglês

10.1002/mrd.22774

1098-2795

Allison R. Grover, Dana Kimelman, Megan A. Runge, Frances E. Duncan,

Microtubule and mitosis dynamics

In vitro maturation (IVM) is the process whereby oocytes arrested in prophase of meiosis I are stimulated to resume meiosis and progress to metaphase of meiosis II (MII) ex vivo. Here we examined the cytoskeletal morphology of mature MII eggs obtained following IVM. Cumulus oocyte complexes were isolated from antral follicles of hyper-stimulated female mice, and cumulus cells were removed to induce spontaneous oocyte meiotic maturation. This article is protected by copyright. All rights reserved