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Middle Ear Infection Postimplantation: Response of the round Window Membrane to Streptococcus Pyogenes

1987; SAGE Publishing; Volume: 96; Issue: 1_suppl Linguagem: Inglês

10.1177/00034894870960s124

1943-572X

Noel Cranswick, Burkhard Franz, Graeme M. Clark, Robert K. Shepherd, D. M. Bloom,

Nasal Surgery and Airway Studies

The seal of the implanted round window membrane to resist Streptococcus pyogenes invasion from the middle ear was investigated in 12 cats. Results showed that the implanted round window membrane is able to form a barrier for S pyogenes starting 1 week postimplantation. Under normal conditions S pyogenes did not pass through the round window membrane, nor through the gap that existed between the membrane and the prosthesis. Mechanical disruption of the round window seal, however, and severe inflammatory response to S pyogenes caused the infection to extend into the inner ear.