Portal de Periódicos da CAPES

Clinical management of genital chronic GvHD

2017; Springer Nature; Volume: 52; Issue: 6 Linguagem: Inglês

10.1038/bmt.2016.315

1476-5365

Betty K. Hamilton, Oluwatosin Goje, Bipin N. Savani, Navneet S. Majhail, Pamela Stratton,

Parvovirus B19 Infection Studies

Chronic GvHD (cGvHD) of the genital tract is an underreported and infrequently recognized complication of allogeneic hematopoietic cell transplantation in both male and female long-term survivors. Its pathophysiology, clinical manifestations and management are not well understood, and studies are limited. We thus provide a comprehensive review of genital cGvHD in both men and women, as well as discuss related issues of sexual health and viral reactivation. We further provide guidance on screening, management and long-term follow-up, as well as future priority areas of study.