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Obesity and recurrent vulvovaginal bacterial infections in women of reproductive age

2017; Oxford University Press; Volume: 93; Issue: 1099 Linguagem: Inglês

10.1136/postgradmedj-2016-134638

1469-0756

Gary Ventolini, Nuvneet Khandelwal, Kathryn Hutton, Jonathan Lugo, Scott E. Gygax, Natalia Schlabritz‐Loutsevitch,

Urinary Tract Infections Management

Obesity, defined as an excessive deposition of body fat, and usually reported as body mass index (BMI) exceeding 30 kg/m2, has been linked to increased morbidity and mortality and has been associated with an increased risk of cancer, cardiovascular diseases, Type II diabetes (DM) and infections.1–5 Obesity is a low-grade inflammatory state,6 7 and adipose tissue is an active immunological organ with increased production of tumour necrosis factor α, interleukin (IL)-1β and IL-6.8 Obesity is associated with an increased susceptibility to infections; however, the results of clinical studies evaluating BMI and vaginitis are controversial.9 The aim of the discussed study was to determine the association between obesity and recurrent vulvovaginal bacterial infections (RVVBI) in women of reproductive age.