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How to measure the net benefit of treatment?

2017; Elsevier BV; Volume: 72; Issue: 1 Linguagem: Inglês

10.1016/j.therap.2016.12.004

1958-5578

François Gueyffier, Pascal Piedbois, Jean‐François Bergmann, Bernard Avouac, Thomas Borel, Rémy Boussageon, Catherine Brun-Strang, David Braunstein, Béatrice Cazeneuve, Marine Diviné, P. Dufour, Nicolas Girerd, Valérie Laigle, Claire Le Jeunne, François Liard, Amélie Marsot, Jean‐Louis Montastruc, Albert Trinh-Duc, Éric Vicaut,

Clinical practice guidelines implementation

Estimating net benefit makes possible to clarify the basis for therapeutic decisions on an individual and collective level. This clarification is a must in shared medical decision-making and evidence-based medicine. Numerous methods are available, although none outweigh the others. The complex specifications of net benefit estimation should be tailored to the expectations of the central stakeholder, patient or society, and the unlimited range of potential contexts. The challenges, limitations, constraints and skills to be acquired by all stakeholders were discussed by the participants of the round table. They are described in this article, enabling key messages and guidelines to be presented. The essential priority is to ensure that all stakeholders receive the required training.