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Using Proton Beam Therapy in the Elderly Population: A Snapshot of Current Perception and Practice

2017; Elsevier BV; Volume: 98; Issue: 4 Linguagem: Inglês

10.1016/j.ijrobp.2017.01.007

1879-355X

Juliette Thariat, Terence T. Sio, Pierre Blanchard, Samir Patel, Yusuke Demizu, Federico L. Ampil, S. Guihard, Robert C. Miller, Ulf Karlsson, Marco Krengli, Huan Giap, Nam P. Nguyen,

Frailty in Older Adults

It is projected that 1 of 5 Americans will be aged ≥65 years in 2050 and that 60% of cancers will occur in this group (http://www.seer.cancer.gov). As proton therapy (PT) resources are limited, several centers have designed their own decision-making systems for prioritization. Although children are well recognized as deriving benefit from PT, much less is known about elderly patients and whether, or when, we should consider the use of PT in this population. For example, the University of Pennsylvania team designed an a-priori resource allocation score during their ramp-up phase in 2010. Their score underestimated proton therapy allocation to older patients ( 1 Bekelman J.E. Asch D.A. Tochner Z. Friedberg J. Vaughn D.J. Rash E. Raksowski K. Hahn S.M. Principles and reality of proton therapy treatment allocation. Int J Radiat Oncol Biol Phys. 2014; 89: 499-508 Abstract Full Text Full Text PDF PubMed Scopus (21) Google Scholar ).