Artigo Acesso aberto Produção Nacional Revisado por pares

International, evidence-based consensus diagnostic criteria for HHV-8–negative/idiopathic multicentric Castleman disease

2017; Elsevier BV; Volume: 129; Issue: 12 Linguagem: Inglês

10.1182/blood-2016-10-746933

ISSN

1528-0020

Autores

David C. Fajgenbaum, Thomas S. Uldrick, Adam Bagg, Dale Frank, David Wu, Gordan Srkalović, David Simpson, Amy Liu, David M. Menke, Shanmuganathan Chandrakasan, Mary Jo Lechowicz, Raymond Wong, Sheila K. Pierson, Michele Paessler, Jean‐François Rossi, Makoto Ide, Jason R. Ruth, Michael P. Croglio, Alexander Suarez, Vera P. Krymskaya, Amy Chadburn, Gisele W. B. Colleoni, Sunita D. Nasta, Raj Jayanthan, Christopher S. Nabel, Corey Casper, Angela Dispenzieri, Alexander Fosså, Dermot Kelleher, Razelle Kurzrock, Peter M. Voorhees, Ahmet Doğan, Kazuyuki Yoshizaki, Frits van Rhee, Éric Oksenhendler, Elaine S. Jaffe, Kojo S.J. Elenitoba‐Johnson, Megan S. Lim,

Tópico(s)

CNS Lymphoma Diagnosis and Treatment

Resumo

Key Points An international panel established the first ever diagnostic criteria for iMCD based on review of 244 clinical cases and 88 tissue samples. The criteria require multicentric lymphadenopathy with defined histopathology, ≥2 clinical/laboratory changes, and exclusion of iMCD mimics.

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