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Toxicology evaluation of selenium protein powder

2017; EDP Sciences; Volume: 8; Linguagem: Inglês

10.1051/bioconf/20170802009

2273-1709

Shunyi Qin, Lina Liu, Jingshen Wang, Fanghong Zhao, Jifei Ma,

Heavy Metal Exposure and Toxicity

The experiment was conducted to evaluate the safety of selenium protein powder, a novel organic selenium nutritional supplement, and reported corresponding data and results based on a series of toxicological tests. It was examined to evaluate oral acute toxicity by median lethal dose test and mutagenic potential by bone marrow cell micronucleus test and sperm abnormality test using Kun-Ming mice. The results showed that the oral LD50 of selenium protein powder exceeded 31.25 g/kg body weight in mice. No mutagenicity was found by mouse bone marrow cell micronucleus test and mouse sperm abnormality test. The results suggested greater safety of selenium protein powder as a nutritional selenium supplement, and selenium protein powder has the potential for development and application in food systems or functional foods.