The Components of Tannic Activities in Labiatae Plants. I. : Rosmarinic Acid from Labiatae Plants in Japan
1986; Pharmaceutical Society of Japan; Volume: 106; Issue: 12 Linguagem: Inglês
10.1248/yakushi1947.106.12_1108
ISSN1347-5231
AutoresTakuo Okuda, Tsutomu Hatano, Isao Agata, Sansei Nishibe,
Tópico(s)Natural product bioactivities and synthesis
ResumoThe main polyphenolic compound in the leaves of Perilla frutescens var. crispa, which is responsible to the tannic activity of the leaf extract, was isolated and identified as rosmarinic acid. Contrary to the phenomena observed for geraniin in geranii herba, a decrease in rosmarinic acid by decomposition was not observed when decoction of perillae folium was continued for 70 min, while rosmarinic acid was decomposed to a large extent when collected leaves were dried at the temperature over 50°C. Rosmarinic acid has also been isolated from the spikes of Prunella vulgaris var. lilacina and from the leaves of Glechoma hederacea var. grandis. The high performance liquid chromatography analysis showed that Agastache rugosa, Isodon japonicus and several Mentha species contain fairly large amount of rosmarinic acid.
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