Produção Nacional
Revisado por pares
PP - CALCIFYING EPITHELIAL ODONTOGENIC TUMOR
2017; Elsevier BV; Volume: 123; Issue: 2 Linguagem: Inglês
10.1016/j.oooo.2016.09.123
ISSN2212-4411
AutoresLetícia Drumond de Abreu Guimarães, GRABRIELA NAGATA, Décio dos Santos Pinto Júnior,
Tópico(s)Tumors and Oncological Cases
ResumoCalcifying epithelial odontogenic tumor (CEOT) is a rare benign odontogenic neoplasm, locally aggressive, characterized by sheets and nests of polyhedral epithelial cells exhibiting eosinophilic cytoplasm or, less often, clear cytoplasm. Additional features include nuclear pleomorphism without mitotic activity, concentric calcifications, and amyloid deposits. This case is an additional example of clear cell variant of CEOT occurring in a 28-year-old male patient, presenting discomfort in the third molar right region. No clinical signs were observed. Image exams revealed a well-delimited unilocular mixed radiolucencent-radiopaque lesion with displacement of bone cortical and teeth. Incisional biopsy was performed and the microscopic examination showed a tumor consisted of proliferation of epithelial cells with eosinophilic, clear vacuolated cytoplasm interspersed with focal areas of amyloid deposition. Tumor cells were immunopositive for AE1/ AE3. Surgical excision was performed, and no tumor recurrence has been observed after three years of follow-up.
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