Revisão Acesso aberto Produção Nacional Revisado por pares

Peritoneal Dialysis Treatment Modality Option in Acute Kidney Injury

2017; Karger Publishers; Volume: 43; Issue: 1-3 Linguagem: Inglês

10.1159/000452703

ISSN

1421-9735

Autores

Daniela Ponce, Mariele Gobo-Oliveira, André Luís Balbi,

Tópico(s)

Cardiac Arrest and Resuscitation

Resumo

It has not been clearly shown which modality of dialysis is superior in the management of acute kidney injury (AKI). Most centers in developed countries have adopted extracorporeal blood purification (EBP) strategies, such as continuous or intermittent forms of hemodialysis or hemofiltration, for the supportive management of AKI. On the other hand, the use of peritoneal dialysis (PD) is widespread in developing countries in view of its ease of use, low cost and minimal requirements on infrastructure. The dose of dialysis required for AKI remains controversial, although an augmented dose with a high small solute clearance is advocated until further definitive evidence becomes available. No studies have directly examined the effects of the dose of PD on outcomes in AKI. The targets of dose for PD are inferred from studies conducted with EBP. There are concerns that PD is unable to achieve high clearances required to support a patient with renal failure. However, various techniques have been described which are able to achieve the targets of small solute clearance. These include high volume PD and continuous flow PD. The selection of flexible peritoneal catheters with better catheter function and dialysate flow rates can improve the efficiency of PD. Other aspects of dose should also be examined, including clearance of middle molecular weight toxins as well as adequate fluid removal. With careful selection of techniques to meet the individual demands of the patient, PD is an appropriate modality of dialysis for patients with AKI.

Referência(s)