Portal de Periódicos da CAPES

Dietary copper affects antioxidant and immune activity in hybrid tilapia ( Oreochromis niloticus × Oreochromis aureus )

2017; Wiley; Volume: 23; Issue: 5 Linguagem: Inglês

10.1111/anu.12468

1365-2095

Lining Tang, Kai Huang, Jun Xie, Daejung Yu, Linlin Sun, Qing Huang, Yuhe Bi,

Fish Biology and Ecology Studies

Aquaculture NutritionVolume 23, Issue 5 p. 1003-1015 ORIGINAL ARTICLE Dietary copper affects antioxidant and immune activity in hybrid tilapia (Oreochromis niloticus × Oreochromis aureus) L. Tang, L. Tang College of Animal Science and Technology, Guangxi University, Nanning, ChinaSearch for more papers by this authorK. Huang, Corresponding Author K. Huang kaihuangnn@163.com College of Animal Science and Technology, Guangxi University, Nanning, China Correspondence Kai Huang, College of Animal Science and Technology, Guangxi University, Nanning, China. Email: kaihuangnn@163.comSearch for more papers by this authorJ. Xie, J. Xie Key Laboratories of Tropical & Subtropical Fishery Resource Application & Cultivation, Ministry of Agriculture, Pearl River Fishery Research Institute, Chinese Academy of Fishery Sciences, Guangzhou, ChinaSearch for more papers by this authorD. Yu, D. Yu Baiyang Group, Nanning High-tech Industry Development Zone, Nanning, ChinaSearch for more papers by this authorL. Sun, L. Sun College of Animal Science and Technology, Guangxi University, Nanning, ChinaSearch for more papers by this authorQ. Huang, Q. Huang College of Animal Science and Technology, Guangxi University, Nanning, ChinaSearch for more papers by this authorY. Bi, Y. Bi College of Animal Science and Technology, Guangxi University, Nanning, ChinaSearch for more papers by this author L. Tang, L. Tang College of Animal Science and Technology, Guangxi University, Nanning, ChinaSearch for more papers by this authorK. Huang, Corresponding Author K. Huang kaihuangnn@163.com College of Animal Science and Technology, Guangxi University, Nanning, China Correspondence Kai Huang, College of Animal Science and Technology, Guangxi University, Nanning, China. Email: kaihuangnn@163.comSearch for more papers by this authorJ. Xie, J. Xie Key Laboratories of Tropical & Subtropical Fishery Resource Application & Cultivation, Ministry of Agriculture, Pearl River Fishery Research Institute, Chinese Academy of Fishery Sciences, Guangzhou, ChinaSearch for more papers by this authorD. Yu, D. Yu Baiyang Group, Nanning High-tech Industry Development Zone, Nanning, ChinaSearch for more papers by this authorL. Sun, L. Sun College of Animal Science and Technology, Guangxi University, Nanning, ChinaSearch for more papers by this authorQ. Huang, Q. Huang College of Animal Science and Technology, Guangxi University, Nanning, ChinaSearch for more papers by this authorY. Bi, Y. Bi College of Animal Science and Technology, Guangxi University, Nanning, ChinaSearch for more papers by this author First published: 30 January 2017 https://doi.org/10.1111/anu.12468Citations: 6Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Abstract Copper (Cu) is an essential nutrition trace element for Tilapia. However, the molecular mechanisms for the effects of Cu on Tilapia remain unknown. To explore the mechanism, 2,160 hybrid tilapia (Oreochromis niloticus × Oreochromis aureus) fries were used and evenly assigned to six groups and fed with different concentrations of Cu. After 60-day culture, physiological characters and biochemical parameters were measured. Spleen somatic index (SSI) was analysed, and distribution of trace elements was investigated. qRT-PCR was used to analyse the levels of immune genes. The result showed that 17 mg kg−1 of dietary Cu improved the growth rate, survival rate (SR), weight gain rate, condition factor and feed conversion ratio of hybrid tilapia (p < .05). Meanwhile, the dietary Cu increased the activity of superoxide dismutase and reduced the activity of glutathione (GSH), alanine aminotransferase, aspartate aminotransferase and lysozyme (p < .05). Sixteen mg kg−1 of dietary Cu did not affect SSI. Furthermore, dietary Cu affects the levels of immune genes, interleukin-1, tumour necrosis factor, MHC class IIB, pre-B-cell leukaemia transcription factor 1 and P450. Therefore, a certain concentration of Cu can improve tilapia performance by affecting its antioxidant and immune activity. Citing Literature Volume23, Issue5October 2017Pages 1003-1015 RelatedInformation