Crystal Structure of an LSD-Bound Human Serotonin Receptor
2017; Cell Press; Volume: 168; Issue: 3 Linguagem: Inglês
10.1016/j.cell.2016.12.033
ISSN1097-4172
AutoresDaniel Wacker, Sheng Wang, John D. McCorvy, Robin M. Betz, AJ Venkatakrishnan, Anat Levit, Katherine Lansu, Zachary L. Schools, Tao Che, David E. Nichols, Brian K. Shoichet, Ron O. Dror, Bryan L. Roth,
Tópico(s)Receptor Mechanisms and Signaling
ResumoThe prototypical hallucinogen LSD acts via serotonin receptors, and here we describe the crystal structure of LSD in complex with the human serotonin receptor 5-HT
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