Improved Survival of Cervical Cancer Patients in a Screened Population in Rural India
2016; National Institutes of Health; Volume: 17; Issue: 11 Linguagem: Inglês
10.22034/apjcp.2016.17.11.4837
AutoresKasturi Jayant, Rengaswamy Sankaranarayanan, Ranjit Thorat, Richard Muwonge, Sanjay Hingmire, Nandkumar Panse, Surendra S. Shastri, Sylla G. Malvi, Bhagwan M. Nene,
Tópico(s)Endometrial and Cervical Cancer Treatments
ResumoObjectives: To describe the survival experience of cervix cancer patients in a screened rural population in India. Methods: Included 558 cervical cancer patients diagnosed in 2000-2013 in a cohort of 100,258 women invited for screening during 2000-2003. The primary end point was death from cervical cancer. We used the Kaplan-Meier method to estimate cumulative observed survival and Cox proportional hazards regression to assess the effect of patient characteristics on survival after diagnosis. Results: Of the 558 cases included, 143 (26%) and 114 (20%) were diagnosed in stages IA and IB respectively; 252 (45.2%) were dead, and 306 (54.8%) were alive at the last follow-up. The overall 5-year observed survival was 60.5%. The 5-year survival of stage IA patients was 95.1% and 5.3% for stage IV patients. All surgically treated stage IA patients, 94.1% of stage IB patients receiving intracavitary radiotherapy, 62% of stage IIB, 49% of stage III and 25% of stage IV patients receiving radiotherapy survived for 5 years. Conclusion: Higher 5-year survival in our study than elsewhere in India is due to the high proportion of early stage cancers detected by screening combined with adequate treatment, resulting into a favourable prognosis.
Referência(s)