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Pathophysiology of the cardio-renal syndromes types 1–5: An uptodate

2017; Elsevier BV; Volume: 69; Issue: 2 Linguagem: Inglês

10.1016/j.ihj.2017.01.005

2213-3763

Luca Di Lullo, Antonio Bellasi, Vincenzo Bàrbera, Domenico Russo, Luigi Russo, Biagio Di Iorio, Mario Cozzolino, Claudio Ronco,

Chronic Kidney Disease and Diabetes

According to the recent definition proposed by the Consensus conference on Acute Dialysis Quality Initiative Group, the term cardio-renal syndrome (CRS) has been used to define different clinical conditions in which heart and kidney dysfunction overlap. Type 1 CRS (acute cardio- renal syndrome) is characterized by acute worsening of cardiac function leading to AKI (5, 6) in the setting of active cardiac disease such as ADHF, while type - 2 CRS occurs in a setting of chronic heart disease. Type 3 CRS is closely link to acute kidney injury (AKI), while type 4 represent cardiovascular involvement in chronic kidney disese (CKD) patients. Type 5 CRS represent cardiac and renal involvement in several diseases such as sepsis, hepato - renal syndrome and immune - mediated diseases.