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Hantavirus infection: a global zoonotic challenge

2017; Elsevier BV; Volume: 32; Issue: 1 Linguagem: Inglês

10.1007/s12250-016-3899-x

1674-0769

Hong Jiang, Xuyang Zheng, Limei Wang, Hong Du, Pingzhong Wang, Xue–Fan Bai,

Viral Infections and Outbreaks Research

Hantaviruses are comprised of tri-segmented negative sense single-stranded RNA, and are members of the Bunyaviridae family. Hantaviruses are distributed worldwide and are important zoonotic pathogens that can have severe adverse effects in humans. They are naturally maintained in specific reservoir hosts without inducing symptomatic infection. In humans, however, hantaviruses often cause two acute febrile diseases, hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS). In this paper, we review the epidemiology and epizootiology of hantavirus infections worldwide.