Produção Nacional
Revisado por pares
Optical coherence tomography as a method for quantitative skin evaluation in systemic sclerosis
2017; BMJ; Volume: 77; Issue: 3 Linguagem: Inglês
10.1136/annrheumdis-2016-210875
ISSN1468-2060
AutoresNatália Sotero Machado Pires, Andréa Tavares Dantas, Ângela Luzia Branco Pinto Duarte, Marcello Magri Amaral, Luana Osório Fernandes, Tereza Januária Costa Dias, Luciana Santos Afonso de Melo, Anderson S. L. Gomes,
Tópico(s)Systemic Lupus Erythematosus Research
ResumoImproved, non-invasive techniques for the diagnosis, classification and monitoring of patients with systemic sclerosis (SSc) are needed. One potential technique for quantifying the extent of cutaneous sclerosis in these patients is optical coherence tomography (OCT).1 ,2 Recently, Abignano et al 3 suggested the use of OCT as a feasible and reliable technique to evaluate skin fibrosis in SSc. Based on that initial work, the aim of this study was to evaluate OCT images and compare the findings with the modified Rodnan skin score (mRSS) in patients with SSc. Thirty-three Brazilian patients with SSc (28 women; mean age 46.1 years; range 19–71 years) were recruited and fulfilled criteria for SSc proposed by American College of Rheumatology (ACR), 19804 or ACR/European League Against Rheumatism, 2013.5 Patients were classified into limited SSc (n=18) and diffuse SSc (n=15) groups. The mean disease duration was 9.7 years (median 8 years, range 2–26 months). Thirty-five healthy control (HC) (28 women, …
Referência(s)