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Neutrophils acquire the capacity for antigen presentation to memory CD4+ T cells in vitro and ex vivo

2017; Elsevier BV; Volume: 129; Issue: 14 Linguagem: Inglês

10.1182/blood-2016-10-744441

1528-0020

Maria Vono, Ang Lin, Anna Norrby‐Teglund, Richard A. Koup, Frank Liang, Karin Loré,

Immune cells in cancer

Key Points Neutrophils can present cognate antigens to antigen-specific memory CD4+ T cells. MHC-II and costimulatory molecules are induced on neutrophils in the presence of antigen and antigen-specific memory CD4+ T cells.