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The 1-min sit-to-stand test in cystic fibrosis — Insights into cardiorespiratory responses

2017; Elsevier BV; Volume: 16; Issue: 6 Linguagem: Inglês

10.1016/j.jcf.2017.01.012

1873-5010

Thomas Radtke, Helge Hebestreit, Milo A. Puhan, Susi Kriemler,

Delphi Technique in Research

We aimed to characterize the cardiopulmonary response during a 1-min sit-to-stand (STS) test and compare peak exercise cardiorespiratory variables to a maximal cardiopulmonary exercise test (CPET) in cystic fibrosis (CF). We further aimed to assess the validity of the STS power index (PowerSTS) as a measure of exercise capacity.Fifteen adult CF patients performed spirometry, CPET and the 1-min STS test with respiratory gas analysis.Peak-exercise cardiorespiratory variables during the 1-min STS test correlated strongly (r=0.69-0.98) with those measured during the CPET. Oxygen uptake, carbon dioxide production, heart rate, ventilation, and tidal volume at peak exercise were 24%, 26%, 9%, 10% and 21% lower in the 1-min STS test, while respiratory frequencies were 14% higher. PowerSTS showed strong to very strong correlations with CPET-derived absolute peak oxygen uptake and maximal workload.The 1-min STS test elicits a substantial but lower cardiorespiratory response compared to a maximal cycle ergometry CPET. While PowerSTS and STS repetitions are both valid outcome measures of functional capacity, STS repetitions are clinically more practical.