Produção Nacional
Revisado por pares
Risk factors for unintentional medication discrepancies at hospital admission: A matched case-control study
2017; Elsevier BV; Volume: 40; Linguagem: Inglês
10.1016/j.ejim.2017.02.003
ISSN1879-0828
AutoresCarina Carvalho Silvestre, Lincoln Marques Cavalcante Santos, Rafaella de Oliveira Santos Silva, Genival Araujo dos Santos Júnior, Sabrina Joany Felizardo Neves, Alfredo Dias de Oliveira‐Filho, Iza Maria Fraga Lôbo, Divaldo Pereira de Lyra,
Tópico(s)Pharmaceutical studies and practices
ResumoUnintentional medication discrepancies (UMD) are defined as erroneous and unjustified medication changes between the medication use history and the admission medication orders. UMD (e.g., medication omissions, incorrect doses, incorrect frequencies of administration, therapeutic duplications, among others) are distinguished from intentional medication discrepancies in which adjustments guided by the patient's clinical condition are made at the time of admission [ [1] Cornish P.L. Knowles S.R. Marchesano R. et al. Unintended medication discrepancies at the time of hospital admission. Arch Intern Med. 2005; 165: 424-429 Crossref PubMed Scopus (749) Google Scholar ]. Previous studies observed that 14.7% to 66.2% of identified UMD at admission or discharge are able to cause potential damage to patients [ 1 Cornish P.L. Knowles S.R. Marchesano R. et al. Unintended medication discrepancies at the time of hospital admission. Arch Intern Med. 2005; 165: 424-429 Crossref PubMed Scopus (749) Google Scholar , 2 Michel B. Quelennec B. Andres E. Medication reconciliation practices and potential clinical impact of unintentional discrepancies. JAMA Intern Med. 2013; 173: 246-247 Crossref PubMed Scopus (8) Google Scholar , 3 Wong J.D. Bajcar J.M. Wong G.G. et al. Medication reconciliation at hospital discharge: evaluating discrepancies. Ann Pharmacother. 2008; 42: 1373-1379 Crossref PubMed Scopus (248) Google Scholar ]. Discrepancies between the medications patients taken before admission and those listed in their admission orders range from 50% to 70% [ 1 Cornish P.L. Knowles S.R. Marchesano R. et al. Unintended medication discrepancies at the time of hospital admission. Arch Intern Med. 2005; 165: 424-429 Crossref PubMed Scopus (749) Google Scholar , 4 Tam V.C. Knowles S.R. Cornish P.L. et al. Frequency, type and clinical importance of medication history errors at admission to hospital: a systematic review. CMAJ. 2005; 173: 510-515 Crossref PubMed Scopus (620) Google Scholar , 5 Pippins J.R. Gandhi T.K. Hamann C. et al. Classifying and predicting errors of inpatient medication reconciliation. J Gen Intern Med. 2008; 23: 1414-1422 Crossref PubMed Scopus (303) Google Scholar , 6 Mixon A.S. Myers A.P. Leak C.L. et al. Characteristics associated with postdischarge medication errors. Mayo Clin Proc. 2014; 89: 1042-1051 Abstract Full Text Full Text PDF PubMed Scopus (52) Google Scholar ]. Several studies have investigated the prevalence of UMD, but few have focused on its causes [ 4 Tam V.C. Knowles S.R. Cornish P.L. et al. Frequency, type and clinical importance of medication history errors at admission to hospital: a systematic review. CMAJ. 2005; 173: 510-515 Crossref PubMed Scopus (620) Google Scholar , 6 Mixon A.S. Myers A.P. Leak C.L. et al. Characteristics associated with postdischarge medication errors. Mayo Clin Proc. 2014; 89: 1042-1051 Abstract Full Text Full Text PDF PubMed Scopus (52) Google Scholar , 7 Unroe K.T. Pfeiffenberger T. Riegelhaupt S. et al. Inpatient medication reconciliation at admission and discharge: a retrospective cohort study of age and other risk factors for medication discrepancies. Am J Geriatr Pharmacother. 2010; 8: 115-126 Abstract Full Text PDF PubMed Scopus (141) Google Scholar ]. Until this date, there are no case-control or cohort studies of risk factors for UMD.
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