Produção Nacional
Revisado por pares
Oropouche Virus: Clinical, Epidemiological, and Molecular Aspects of a Neglected Orthobunyavirus
2017; American Society of Tropical Medicine and Hygiene; Volume: 96; Issue: 5 Linguagem: Inglês
10.4269/ajtmh.16-0672
ISSN1476-1645
AutoresJ. F. Travassos da Rosa, William Marciel de Souza, Francisco de Paula Pinheiro, Mário Luiz Figueiredo, Jedson Ferreira Cardoso, Gustavo Olszanski Acrani, Márcio Roberto Teixeira Nunes,
Tópico(s)Mosquito-borne diseases and control
ResumoAbstractOropouche virus (OROV) is an important cause of arboviral illness in Latin American countries, more specifically in the Amazon region of Brazil, Venezuela and Peru, as well as in other countries such as Panama. In the past decades, the clinical, epidemiological, pathological, and molecular aspects of OROV have been published and provide the basis for a better understanding of this important human pathogen. Here, we describe the milestones in a comprehensive review of OROV epidemiology, pathogenesis, and molecular biology, including a description of the first isolation of the virus, the outbreaks during the past six decades, clinical aspects of OROV infection, diagnostic methods, genome and genetic traits, evolution, and viral dispersal.
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