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A case of lupus-like syndrome in a patient receiving adalimumab and a brief review of the literature on drug-induced lupus erythematosus

2017; Wiley; Volume: 42; Issue: 3 Linguagem: Inglês

10.1111/jcpt.12506

1365-2710

Iva Lomicová, D. Suchý, Karel Pizinger, Petra Cetkovská,

Inflammatory Bowel Disease

What is known and objective Drug-induced lupus erythematosus occurs with some drugs and resolves with their withdrawal. Anti-TNF therapies have been found to be associated with a lupus-like syndrome, which is clinically distinct from classical drug-induced as well as idiopathic lupus erythematosus. Case description We describe a case of a patient with severe psoriasis, who developed muscle pain with paraesthesia accompanied by ANA titres elevation with adalimumab treatment. The condition resolved after adalimumab cessation, and the patient was started on ustekinumab with good results. What is new and conclusion Ustekinumab might be a useful treatment option for patients with a history of TNF-induced lupus-like syndrome.