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BIBTEX RIS

Chemical Composition and Antimicrobial Activity of the Essential Oil of Artemisia absinthium Asteraceae Leaves

2017; Taylor & Francis; Volume: 20; Issue: 1 Linguagem: Inglês

10.1080/0972060x.2016.1257370

ISSN

0976-5026

Autores

Tatiana M. Vieira, Herbert Júnior Dias, Talita C. T. Medeiros, Carlismari O. Grundmann, Milton Groppo, Vladimir Constantino Gomes Heleno, Carlos Henrique Gomes Martins, Wilson Roberto Cunha, Antônio Eduardo Miller Crotti, Eliane de Oliveira Silva,

Tópico(s)

Sesquiterpenes and Asteraceae Studies

Resumo

This study reports on the chemical composition and antimicrobial activity of the essential oil from Artemisia absinthium L. leaves AA EO collected in Brazil against a representative panel of cariogenic bacteria. The minimum inhibitory concentrations MICs were determined by the broth dilution method in 96-well microplates. AA EO was inactive against most of the investigated oral pathogens, but it displayed moderate activity against Streptococcus mutans MIC = 250 μg/mL and very promising activity against Streptococcus mitis MIC = 62.5 μg/mL. Gas chromatography GC FID and gas chromatography mass spectrometry GC-MS revealed that camphor 1, 19.0 %, E-caryophyllene 2, 9.3 %, eucalyptol 3, 6.8 %, germacrene D 6.7 %, and α-cadinol 6.5 % were the major chemical constituents of AA EO. However, when tested alone, compounds 1, 2, and 3 were inactive MIC > 1000 μg/mL against all the studied microorganisms.

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