Endothelial CD99 supports arrest of mouse neutrophils in venules and binds to neutrophil PILRs
2017; Elsevier BV; Volume: 129; Issue: 13 Linguagem: Inglês
10.1182/blood-2016-08-733394
ISSN1528-0020
AutoresDebashree Goswami, Sigrid März, Yu‐Tung Li, Annette Artz, Kerstin Schäfer, Ruth Seelige, Mariana Pacheco‐Blanco, Jing Ding, M. Gabriele Bixel, Masatake Araki, Kimi Araki, Ken‐ichi Yamamura, Dietmar Vestweber,
Tópico(s)Immune Response and Inflammation
ResumoKey Points Only CD99 on endothelial cells, not on neutrophils, participates in neutrophil extravasation in vivo. A new function was found for CD99: support of chemokine-induced β2-integrin activation and neutrophil arrest by binding to PILR.
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