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Ph-activated nano-amorphous calcium phosphate-based cement to reduce dental enamel demineralization

2017; Informa; Volume: 45; Issue: 8 Linguagem: Inglês

10.1080/21691401.2017.1290644

2169-141X

Mary Anne S. Melo, Michael D. Weir, Vanara Florêncio Passos, M. Powers, Hockin H.K. Xu,

Dental Erosion and Treatment

Enamel demineralization is destructive, esthetically compromised, and costly complications for orthodontic patients. Nano-sized amorphous calcium phosphate (NACP) has been explored to address this challenge. The 20% NACP-loaded ortho-cement notably exhibited favorable behavior on reducing demineralization of enamel around brackets in a caries model designed to simulate the carious attack. The 20% NACP-loaded ortho-cement markedly promotes higher calcium and phosphate release at a low pH, and the mineral loss was almost two fold lower and carious lesion depth decreased the by 1/3. This novel approach is promising co-adjuvant route for prevention of dental caries dissemination in millions of patients under orthodontic treatment.