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Bullous pemphigoid of infancy – report and review of infantile and pediatric bullous pemphigoid

2017; University of California, Davis; Volume: 23; Issue: 2 Linguagem: Inglês

10.5070/d3232033972

1087-2108

Bárbara Roque Ferreira, Ana S Vaz, Leonor Ramos, José Pedro Reis, Margarida Gonçalo,

Coagulation, Bradykinin, Polyphosphates, and Angioedema

A 4-month-old infant was observed with an acute itchy bullous dermatosis, predominantly involving the extremities, which revealed a dermal infiltrate rich in eosinophils, C3 deposits at the dermalepidermal junction, and circulating antibodies to BP180 antigen, confirming the diagnosis of bullous pemphigoid. He was initially treated with deflazacort 1 mg/kg/day, further increased to 2 mg/ kg/day, followed by reduction over seven weeks with complete clinical resolution within this period. We discuss epidemiology, etiology, relationship with vaccination, clinical features, and treatment of thisrelatively rare bullous dermatosis in the pediatric age.