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Use of a Vaginal Ring Containing Dapivirine for HIV-1 Prevention in Women

2016; Lippincott Williams & Wilkins; Volume: 71; Issue: 8 Linguagem: Inglês

10.1097/01.ogx.0000489577.60775.40

1533-9866

Jared M. Baeten, Thesla Palanee‐Phillips, Elizabeth R. Brown, Katie Schwartz, Lydia Soto‐Torres, Vaneshree Govender, Nyaradzo Mgodi, Flavia Matovu Kiweewa, Gonasagrie Nair, Felix Mhlanga, Samantha Siva, Linda‐Gail Bekker, Nitesha Jeenarain, Zakir Gaffoor, Francis Martinson, Bonus Makanani, Arendevi Pather, Logashvari Naidoo, Marla Husnik, Barbra A. Richardson, Urvi M. Parikh, John W. Mellors, Mark A. Marzinke, Craig W. Hendrix, Ariane van der Straten, Gita Ramjee, Zvavahera M. Chirenje, Clemensia Nakabiito, Taha E. Taha, Judith Jones, Ashley J. Mayo, Rachel Scheckter, Jennifer Berthiaume, Edward Livant, Cindy Jacobson, Patrick Ndase, Rhonda White, Karen Patterson, Donna Germuga, Beth Galaska, Katherine Bunge, Devika Singh, Daniel Szydlo, Elizabeth Montgomery, Barbara Mensch, Kristine Torjesen, Cynthia I. Grossman, Nahida Chakhtoura, Annaléne Nel, Zeda Rosenberg, Ian McGowan, Sharon L. Hillier,

HIV, Drug Use, Sexual Risk

(Abstracted from N Engl J Med 2016; DOI: 10.1056/NEJMoa1506110) The objective of this study was to examine the efficacy of dapivirine vaginal rings in providing protection against human immunodeficiency virus type 1 (HIV-1). HIV-1 infection incidence is one of the highest in sub-Saharan Africa.