Association study of APOE, LPL and NOS3 polymorphisms with the risk of common cardio pathology in children and pregnant women
2011; Volume: 9; Issue: 4 Linguagem: Inglês
10.17816/ecogen9425-34
ISSN2411-9202
AutoresАndrey S. Glotov, Elena S. Vashukova, Maria D Kanaeva, Maria O Dvoeglazova, Maria M. Danilova, Vladimir S. Pakin, Ekaterina Yu Marochkina, Dina Rustemovna Bicmullina, Maria A Glebova, Ирина Александровна Махрова, Г. И. Образцова, Oleg S. Glotov, М. С. Зайнулина, Tatyana E Ivashchenko, В. С. Баранов,
Tópico(s)Gestational Diabetes Research and Management
ResumoPolymorphisms of APOE (E2/E3/E4), LPL (1595CG) and NOS3 (-786TC) in groups of pregnant women with and without preeclampsia, in donors, in children with hypertension, children with obesity and metabolic syndrome, and in control children were studied by PCR /RF LP analysis. Statistically significant increase of T/C genotype frequency of NOS3 in pregnant women with preeclampsia as well as in women with physiological pregnancy compared to this one in nonpregnant women of donors group was assessed (56%, 59% and 37%, respectively, F0.03).
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