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Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis

2017; Elsevier BV; Volume: 152; Issue: 8 Linguagem: Inglês

10.1053/j.gastro.2017.02.038

1528-0012

Tobias J. Weismüller, Palak Trivedi, Annika Bergquist, Mohamad Imam, Henrike Lenzen, Cyriel Y. Ponsioen, Kristian Holm, Daniel Gotthardt, Martti Färkkilâ, Hanns‐Ulrich Marschall, Douglas Thorburn, Rinse K. Weersma, Johan Fevery, Tobias Mueller, Olivier Chazouillères, Kornelius Schulze, Konstantinos N. Lazaridis, Sven Almér, Stephen P. Pereira, Cynthia Levy, Andrew L. Mason, Sigrid Næss, Christopher L. Bowlus, Annarosa Floreani, Emina Halilbasic, Kidist Yimam, Piotr Milkiewicz, Ulrich Beuers, Dep Huynh, Albert Parés, Christine N. Manser, George Ν. Dalekos, Bertus Eksteen, Pietro Invernizzi, Christoph P. Berg, Gabi I. Kirchner, Christoph Sarrazin, Vincent Zimmer, Luca Fabris, Felix Braun, Marco Marzioni, Brian D. Juran, Karouk Said, Christian Rupp, Kalle Jokelainen, M Valle, Francesca Saffioti, Angela Cheung, Michael Trauner, Christoph Schramm, Roger W. Chapman, Tom H. Karlsen, Erik Schrumpf, Christian P. Strassburg, Michael P. Manns, Keith D. Lindor, Gideon M. Hirschfield, Bettina E. Hansen, Kirsten Muri Boberg,

Liver Disease Diagnosis and Treatment

Primary sclerosing cholangitis (PSC) is an orphan hepatobiliary disorder associated with inflammatory bowel disease (IBD). We aimed to estimate the risk of disease progression based on distinct clinical phenotypes in a large international cohort of patients with PSC.