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Use of the Instantaneous Wave-free Ratio or Fractional Flow Reserve in PCI

2017; Massachusetts Medical Society; Volume: 376; Issue: 19 Linguagem: Inglês

10.1056/nejmoa1700445

1533-4406

Justin E. Davies, Sayan Sen, Hakim‐Moulay Dehbi, Rasha Al‐Lamee, Ricardo Petraco, Sukhjinder Nijjer, Ravinay Bhindi, Sam J. Lehman, D. Walters, James Sapontis, Luc Janssens, Christiaan Vrints, Ahmed Khashaba, Mika Laine, Éric Van Belle, Florian Krackhardt, Waldemar Bojara, Olaf Göing, Tobias Härle, Ciro Indolfi, Giampaolo Niccoli, Flavo Ribichini, Nobuhiro Tanaka, Hiroyoshi Yokoi, Hiroaki Takashima, Yuetsu Kikuta, Andrejs Ērglis, Hugo Vinhas, Pedro Canas Silva, Sérgio Bravo Baptista, Ali Alghamdi, Farrel Hellig, Bon–Kwon Koo, Chang‐Wook Nam, Eun‐Seok Shin, Joon‐Hyung Doh, Salvatore Brugaletta, Eduardo Alegría‐Barrero, Martijin Meuwissen, Jan J. Piek, Niels van Royen, Murat Sezer, Carlo Di Mario, Robert Gerber, Iqbal Malik, Andrew S.P. Sharp, Suneel Talwar, Kare Tang, Habib Samady, John D. Altman, Arnold H. Seto, Jasvindar Singh, Allen Jeremias, Hitoshi Matsuo, Rajesh Kharbanda, Manesh R. Patel, Patrick W. Serruys, Javier Escaned,

Antiplatelet Therapy and Cardiovascular Diseases

Coronary revascularization guided by fractional flow reserve (FFR) is associated with better patient outcomes after the procedure than revascularization guided by angiography alone. It is unknown whether the instantaneous wave-free ratio (iFR), an alternative measure that does not require the administration of adenosine, will offer benefits similar to those of FFR.