Geospatial Resolution of Human and Bacterial Diversity with City-Scale Metagenomics
2015; Elsevier BV; Volume: 1; Issue: 1 Linguagem: Inglês
10.1016/j.cels.2015.07.006
ISSN2639-5460
AutoresEbrahim Afshinnekoo, Cem Meydan, Shanin Chowdhury, Dyala Jaroudi, Collin Boyer, Nick Bernstein, Julia M. Maritz, Darryl Reeves, Jorge Gandara, Sagar Chhangawala, Sofia Ahsanuddin, Amber Simmons, Timothy Nessel, Bharathi Sundaresh, Elizabeth Pereira, Ellen Jorgensen, Sergios‐Orestis Kolokotronis, Nell Kirchberger, Isaac Garcia, David R. Gandara, Sean Dhanraj, Tanzina Nawrin, Yogesh Saletore, Noah Alexander, Priyanka Vijay, Elizabeth Hénaff, Paul Zumbo, Michael Walsh, G. D. O’Mullan, Scott Tighe, Joel T. Dudley, Anya Dunaif, Sean Ennis, Eoghan O’Halloran, Tiago R. Magalhães, Braden Boone, Angela Jones, Theodore R. Muth, Katie Schneider Paolantonio, Elizabeth Alter, Eric E. Schadt, Jeanne Garbarino, Robert J. Prill, Jane M. Carlton, Shawn Levy, Christopher E. Mason,
Tópico(s)Metabolomics and Mass Spectrometry Studies
Resumo(Cell Systems 1, 72–87; July 29, 2015) Figure 3B has been corrected to show the general coverage of the Yersinia pestis pMT1 plasmid, but not the murine toxin gene (yMT). The initial claim of “…consistent 20× coverage across the murine toxin gene…” was erroneously based on looking at gene annotation coordinates from different reference sequences. No reads mapped to the yMT gene when updated annotations were used. The Summary, Results, and Discussion sections have been revised to remove and clarify misleading and speculative text about pathogenic organisms. We now state that although all our metagenomic analysis tools identified reads with similarity to B. anthracis and Y. pestis sequences, there is minimal coverage to the backbone genome of these organisms, and there is no strong evidence to suggest these organisms are in fact present, and no evidence of pathogenicity. The figure and the text have been corrected online and in the print version. Geospatial Resolution of Human and Bacterial Diversity with City-Scale MetagenomicsAfshinnekoo et al.Cell SystemsMarch 3, 2015In BriefAfshinnekoo et al. describe a city-scale molecular profile of DNA collected from a city's subway system, public surfaces, and one waterway. These data enable a baseline analysis of bacterial, eukaryotic, and aracheal organisms in the built environment of mass transit and urban life. Full-Text PDF Open Access
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