
The muscarinic effect of anhydroecgonine methyl ester, a crack cocaine pyrolysis product, impairs melatonin synthesis in the rat pineal gland
2017; Oxford University Press; Volume: 6; Issue: 4 Linguagem: Inglês
10.1039/c7tx00009j
ISSN2045-4538
AutoresLívia Silva Medeiros de Mesquita, Raphael Caio Tamborelli Garcia, Fernanda Gaspar do Amaral, Rafael Peres, Simone Miller Wood, RodrigoVincenzo de Luca Lucena, Eduardo Osório Frare, Mariana Abrahão, Tânia Marcourakis, José Cipolla‐Neto, Solange Castro Afeche,
Tópico(s)Neurotransmitter Receptor Influence on Behavior
ResumoAEME impaired melatonin synthesis both in vivo and in vitro and this effect seems to be mediated by muscarinic receptors and [Ca 2+ ]i elevation.
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