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Poly(hydroxybutyrate‐ co ‐hydroxyvalerate) and bovine serum albumin blend prepared by electrospinning

2017; Wiley; Volume: 134; Issue: 29 Linguagem: Inglês

10.1002/app.45090

1097-4628

Elizaveta R. Pavlova, Dmitry V. Bagrov, М. Н. Копицына, Dmitry A. Shchelokov, А. П. Бонарцев, И. И. Жаркова, T.K. Mahina, В. Л. Мышкина, Г. А. Бонарцева, К. В. Шайтан, Dmitry V. Klinov,

Advanced Sensor and Energy Harvesting Materials

ABSTRACT Electrospinning is a method for the preparation of nanosized polymer fibers. Here, electrospinning is used to prepare a blend of a polyester, poly(hydroxybutyrate‐ co ‐hydroxyvalerate) (PHBV), and a globular protein, bovine serum albumin (BSA). The electrospun blend film is compared with a solution‐cast blend film and with single‐component electrospun films made of PHBV and BSA. In the electrospun blend films, BSA manifests itself as flat ribbons and a fine network formed from fibers less than 50 nm in diameter. The dissolution rate of BSA from the electrospun blended film is lower than from the solution‐cast one. The films are characterized using scanning electron microscopy, differential scanning calorimetry, and contact‐angle measurements. The obtained PHBV+BSA blend films have several emergent properties: a slow BSA dissolution rate, a fine BSA network, and unusual thermal behavior. Thus, the PHBV+BSA blend films introduce a new class of polymer–protein blends. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017 , 134 , 45090.