
Carotid intima-media thickness is associated with media rather than intima thickness
2017; Elsevier BV; Volume: 261; Linguagem: Inglês
10.1016/j.atherosclerosis.2017.03.033
ISSN1879-1484
AutoresAmanda Veiga Sardeli, Arthur Fernandes Gáspari, Guilherme de Rossi, Giovana Vergínia de Souza, Thiago Mattos Frota de Souza, Cláudia Regina Cavaglieri, José R. Matos‐Souza, Wilson Nadruz, Mara Patrícia Traina Chacon‐Mikahil,
Tópico(s)Heart Rate Variability and Autonomic Control
ResumoIn an interesting study published in January, 2017, Bos et al. [ [1] Bos S. Duvekot M.H. Ten Kate G.R. et al. Carotid artery plaques and intima medial thickness in familial hypercholesteraemic patients on long-term statin therapy: a case control study. Atherosclerosis. 2017; 256: 62-66 Abstract Full Text Full Text PDF PubMed Scopus (22) Google Scholar ] showed that carotid intima-media thickness (C-IMT) did not associate with coronary calcification in statin-treated familial hypercholesterolemia patients. The authors therefore suggested that C-IMT might not be a useful marker for assessing cardiovascular risk and subclinical atherosclerosis in asymptomatic individuals. Carotid artery plaques and intima medial thickness in familial hypercholesteraemic patients on long-term statin therapy: A case control studyAtherosclerosisVol. 256PreviewStatins reduce subclinical atherosclerosis and premature atherosclerotic cardiovascular disease (ASCVD) in patients with familial hypercholesterolemia (FH). However, some FH patients still develop ASCVD despite statin therapy. We compared subclinical atherosclerosis assessed by carotid plaque presence and intima media thickness (C-IMT), in long-term statin-treated FH patients and healthy controls. Furthermore, we analysed whether carotid ultrasonography findings associated with subclinical coronary atherosclerosis. Full-Text PDF
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