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Recombinant Protein Expression in E. coli : A Historical Perspective

2017; Springer Science+Business Media; Linguagem: Inglês

10.1007/978-1-4939-6887-9_1

1940-6029

O. Gileadi,

Bacterial Genetics and Biotechnology

This introductory chapter provides a brief historical survey of the key elements incorporated into commonly used E. coli-based expression systems. The highest impact in expression technology is associated with innovations that were based on extensively studied biological systems, and where the tools were widely distributed in the academic community.