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1P297 Development of methods for labeling and oligomerization analysis of membrane proteins in live cells(27. Bioimaging,Poster)

2013; Physical Society of Japan; Volume: 53; Issue: supplement1-2 Linguagem: Inglês

10.2142/biophys.53.s155_2

1347-4219

Yoshiaki Yano, Kenichi Kawano, Kaoru Omae, Sayaka Mtsuzaki, Katsumi Matsuzaki,

Biotin and Related Studies

Through studies using Imaging Mass Spectrometry (IMS), we could successfully reveal key molecules and their distributions in various biological phenomena and diseases.On the other hand, we also found that these molecules usually behave not independently but relating to other molecules.To characterize the difference of IMS data taking account such interactions, we introduced Shannon entropy to overview mass spectra varied from position-to-position.In our previous presentation in this biophysical society, we discussed characteristic spatial distribution of Shannon entropy in mouse brain irrespective to anatomical representation.In this study, we will present which types of signals are dominant in Shannon entropy estimation and how they contribute to its variation.