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BIBTEX RIS

Nickel-Catalyzed Reductive Dicarbofunctionalization of Alkenes

2017; American Chemical Society; Volume: 139; Issue: 20 Linguagem: Inglês

10.1021/jacs.7b03195

ISSN

1943-2984

Autores

Andrés Garcı́a-Domı́nguez, Zhaodong Li, Cristina Nevado,

Tópico(s)

Asymmetric Hydrogenation and Catalysis

Resumo

An intermolecular, three-component reductive dicarbofunctionalization of alkenes is presented here. The combination of Ni catalysis with TDAE as final reductant enables the direct formation of Csp3–Csp3 and Csp3–Csp2 bonds across a variety of π-systems using two different electrophiles that are sequentially activated with exquisite selectivity under mild reaction conditions.

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